PHIL’S BLOG
Get the lowdown on the latest research and thinking from the world of health and nutrition.
Alzheimer’s disease can be Influenced by Your Diet! Find out More!
In the absence of effective therapies against Alzheimer's disease (AD), the identification of modifiable risk/protective factors is important.
Cauda Equina Syndrome. When a Herniated Disc Becomes a Medical Emergency. Also a New Home Test Kit for Prostate Cancer.
Some degree of nerve compression is likely when there is a prolapsed or herniated intervertebral disc although the extreme compression that causes CES is very unlikely. However if it does occur it is a medical emergency.
New Prospective Treatment Options for Endometriosis
Endometriosis is estimated to affect 176 million women worldwide and there is a significant unmet requirement for treatment options for this condition.
Blood Clot Risk & COVID-19 Vaccines & the New HIV Vaccine
Adenovirus based COVID-19 vaccines and blood clot risk. Phase I trial results for a new vaccine released from IAVI (International AIDS Vaccine Initiative) and the Scripps Research Institute in the U.S. appear promising.
March is Endometriosis Awareness Month
Endometriosis affects 10% of women (or 1.5 million people in the UK) and yet bizarrely takes an average of seven to eleven years to diagnose.
What is a Healthy Diet? How Much Fruit or Veg Should We Eat?
The latest research on healthy eating is by the American Heart Association proves that eating about five daily servings of fruits and vegetables, in which 2 are fruit and 3 are vegetables, appears to be the optimal required for a longer life.
The NaV1.7 Gene: Could Gene Therapy be a Better Alternative to Painkillers?
Gene therapy for chronic pain could offer huge benefits and potential because it would deliver a safer, non-addictive alternative to opioids.
Little Foot: The New Discovery in Human Evolution
In June 2019 in great secrecy ‘Little Foot’ was transported to the UK to be examined in microscopic detail using the ‘Diamond Light Source’ at the national synchrotron facility in the UK.
Alphafold: The First Artificial Intelligence Program that can Predict How Proteins Organise Themselves
A key scientific holy grail has been to accurately predict and understand how proteins fold and tangle themselves into the shapes that hold the key to how they carry out their vital functions (like Watson and Crick’s double helix).
A Malaria Vaccine is being Developed and Trialled
Many more people will die in Africa from malaria than COVID-19 in 2021. Malaria killed 409 000 people in 2019 and 411 000 in 2018, most of them babies and toddlers in sub-Saharan Africa.
The Emerging Threat of Fungi: Candida auris & Aspergillus fumigatus
COVID-19 has stimulated our surveillance of any other possible future threats to our well-being. As we wage war against viruses and bacteria there is also a third organism which is emerging.
COVID-19 Variants: South Africa Variant B.1.351 & the E484K Mutation
The South African variant emerged after the first epidemic wave in a heavily infected metropolitan area, Nelson Mandela Bay, located on the coast of the Eastern Cape Province.
Pfizer Vaccine Rollout in Israel: The First International Test Case
With what is a small population, highly digitized health system, and quick, military-assisted Pfizer vaccine rollout, Israel’s real-world data is an extremely useful addition to clinical trials that can be used by researchers, pharmaceutical companies and policymakers.
Why is the EU Vaccine Rollout so slow Compared to the UK?
The EU Commission, responsible for vaccine procurement, has come under fire, particularly from Germany.
Multiple Sclerosis: Research has been affected by the Pandemic, but there has been Positive Progress
There have been positive scientific breakthroughs that provide new hope for millions of people living with multiple sclerosis.
B.1.1.7: the New Kent Variant of COVID-19 Explained
According to the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) the new variant, which has two names, B.1.1.7 or VUI 202012/01, is 71% more transmissible than any other variant.
Chemotherapy drugs from Brassicas and Yew Trees!
Plant metabolites have a huge range of biological functions and more than 60% of drugs with anti-cancer activity are derived from plants. More recently the brassica family has been an area of strong scientific enquiry.
Air Pollution, PM 2.5 levels and Our Health
This week in the UK there was a landmark legal case that identified air pollution as a cause of death.
mRNA Vaccines can be Developed Quickly, are Easily Adaptive and Cost-Effective
mRNA vaccine production is simple and laboratory based, can be easily adapted and is more cost-effective, which are important considerations for a global pandemic.
mRNA Vaccines and the Logistics of Distribution
Most vaccines are refrigerated at around 2-8°C but Pfizer’s vaccine, which uses messenger RNA, has vastly different requirements. Messenger RNA (or mRNA) vaccines have never been used before but unfortunately they are not thermostable.